Negative Effects

Sources of

Role in Human Health

Manganese

Activates numerous enzymes Catalyzes synthesis of fatty acids and cholesterol Foundation of thyroxin

Whole grain cereals, egg yolks, nuts, seeds, green vegetables, water, supplements

Early: weakness, irritability, intellectual deficits, mood changes, compulsive behavior, inappropriate laughter Later: Parkinson’s like illness, mask-like face, limb rigidity, gait disturbance, slurred speech, excessive salivation and sweating, poor balance ? Irreversible